[Histonet] RE: Mysterious artifact on GI biopsies H&E stain

[Weems, Joyce]

I would check to see what medication the patient was on or if something was done during the procedure to affect the biopsies..

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Urim, Lyudmila
Sent: Monday, April 26, 2010 07:24
To: histonet <@t> lists.utsouthwestern.edu
Subject: [Histonet] Mysterious artifact on GI biopsies H&E stain



> Hi,
> 
> We have been getting a similar staining artifact on some GI biopsies 
> randomly while the rest GI biopsies look fine.
>  Also on the affected GI biopsies there is often only 1 or 2 spots of 
> the biopsy that are affected while the rest of the biopsy looks fine.
> The artifact is being reproduced on each cut; also the artifact 
> doesn't disappear after the affected biopsies get reprocessed.
> The artifact can be described as a foggy, smudgy stain, with deformed 
> nucleus and not enough cell details.
> All our specimens are fixed in 10%NBF.
> 
> Please let me know if you have any ideas.
> Lucy
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