[Histonet] Re: Silver Nitrate instead of inking??
llewllew <@t> shaw.ca
Fri Dec 18 15:24:04 CST 2009
I did work in a lab that used silver nitrate to mark cervical biopsies.
Most of the pathologists used a 1% solution, often dipping the whole cervix
into it and causing the whole lot to precipitate from the formalin (grrr).
One used four or five silver nitrate sticks by dipping in water and just
rubbing over the specimen. It does work, a black porecipitate coating the
edge. I have never heard of any safety concerns with it as the specimen was
placed back into formalin immediately after the coating for processing and
reduction seems to be total. What I did note was that the silver nitrate
sometimes penetrated the tissue and you could see s rim of fine granules
about a cell deep into the surface which could be distracting.
I then got them to switch to India ink, but I found that messy, so I
switched again to Blueing, which was relatively clean and convenient. I
also obtained some tattoo inks so different surfaces could be marked if
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