[Histonet] Bone marrow trephine decalcification

[Georgina Gibson]

Hi Manahil,

I look after our pathology products for Merck Life Science.

We have a great gentle ready to use decal (EDTA based) many people use for Bone Marrow Trephines which gives good results for when need to do molecular work.

It is one of our bestselling products in Australia.

The bone marrow floats to the top once reaches the end point too.

I am not sure if allowed to send product information here, please feel free to email me directly and I can give you more info if interested.


Regards



Georgina Gibson



Field Application Specialist – Tissue Diagnostics and Flavours & Fragrances

Life Science | Solution Scientists



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Merck Life Science Pty Ltd | Ground Floor, Building 1 | 885 Mountain Highway | Bayswater | VIC 3153 | Australia

Mobile: +61 (0)438 201 101 | E-mail: georgina.gibson at merckgroup.com<mailto:georgina.gibson at merckgroup.com> | Web: www.merck.com.au<http://www.merck.com.au/>

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________________________________
From: MANAHIL EL BIREIR via Histonet <histonet at lists.utsouthwestern.edu>
Sent: Thursday, May 29, 2025 6:09:19 PM
To: histonet at lists.utsouthwestern.edu <histonet at lists.utsouthwestern.edu>
Subject: [Histonet] Bone marrow trephine decalcification




I hope this email finds you well.



I am reaching  out regarding the optimisation of our bone marrow trephine specimen decalcification process. Currently, we are utilizing a ready-to-use acid rapid decalcification method. However, our Molecular Department has observed that the acid affects the quality of molecular results.



To enhance our process and ensure optimal molecular sequencing outcomes, we would greatly appreciate it if you could share your bone marrow trephine decalcification protocol with us. Additionally, which decalcification reagent you use to mitigate potential adverse effects on molecular analysis.



Kind regards,



Manahil





Sent from my iPhone

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