[Histonet] Xylene substitutes

Mac Donald, Jennifer jmacdonald at mtsac.edu
Tue Jul 23 20:34:57 CDT 2024


Pros:  aliphatic hydrocarbons are almost odorless and much safer than xylene
Cons:  they take a little longer to clear than xylene and they are not compatible with all mounting media

-----Original Message-----
From: Jacque Sagasser via Histonet <histonet at lists.utsouthwestern.edu>
Sent: Thursday, July 18, 2024 6:38 AM
To: Histonet <histonet at lists.utsouthwestern.edu>
Subject: [Histonet] Xylene substitutes

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Good morning

My lab is thinking about switching to a xylene substitute to reduce the smell and toxicity being emitted from the lab. Could someone discuss the best alternatives to produce optimal results for colon and esophagus biopsies? What are the pros and cons of each?

Thank you,

​Jacque R. Sagasser, HT (ASCP)cm
Gandhi GI Pathology, LLC
999 Brubaker Drive
Suite 1
Kettering OH 45429
jsagasser at gandhigi.com
937-795-1099 phone
937-519-1321 fax
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