[Histonet] Warm formalin

[Hobbs, Carl]

You a re right, Lynette
De rigueur for Diagnostic labs!
My apologies for forgetting that ( I am now in research labs where...it is less restricted, unfortunately).
Essential to be well-documented/adherent to SOPs.
Respectful-illy

Carl


Carl Hobbs FIBMS
Histology and Imaging Manager
Wolfson CARD
Guys Campus, London Bridge 
Kings College London
London
SE1 1UL
 

020 7848 6813


From: Lynette Pavelich <lynettepav at gmail.com>
Sent: 22 July 2020 19:19
To: Hobbs, Carl <carl.hobbs at kcl.ac.uk>
Cc: histonet at lists.utsouthwestern.edu <histonet at lists.utsouthwestern.edu>
Subject: Re: [Histonet] Warm formalin 
 
I would suggest to always refer to your reagent’s IFU insert. This will advise at what temperature you should use/store. All inspectors (CAP, JC, CLIA, etc.) will make you adhere to these specifications. 
Unless you do a well documented validation study that goes outside of these restrictions from the IFU that proves no patient harm, you honestly must go by the IFU recommendations. This would apply to all of our stains/reagents/solutions/antibodies.
Our world is becoming more restrictive……

hope this helps,
Lynette Pavelich, HT(ASCP), QIHC


> On Jul 22, 2020, at 1:55 PM, Hobbs, Carl via Histonet <histonet at lists.utsouthwestern.edu> wrote:
> 
> Depends on what you are doing with the sections.
> IHC or just dye -staining?
> Sure...too hot ( cooking) is not recommended, as stated
> Also stated is that high -temp fixation may also be used with no deleterious effects as long as the fixation time is not extended.
> However, RT -ish even for a week won't be a problem...imho
> Needs must?
> 
> 
> 
> Carl Hobbs FIBMS
> Histology and Imaging Manager
> Wolfson CARD
> Guys Campus, London Bridge 
> Kings College London
> London
> SE1 1UL
>  
> 
> 020 7848 6813
> _______________________________________________
> Histonet mailing list
> Histonet at lists.utsouthwestern.edu
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