[Histonet] Formalin fixation for COVID-19 positive tissues .....

[Tony Henwood (SCHN)]

Hi Richard,

It will depend on the size of the tissue and the source.
Lung tissue is the major concern. Other tissues not affected as much (based on the burgeoning literature on Covid-19).
Routine fixation time are applicable, remembering that the alcohols and heated wax will also inactivate the virus (triple whammy).
I suppose that I better add a reference:

https://www.tandfonline.com/doi/full/10.1080/01478885.2020.1734718


-----Original Message-----
From: Cartun, Richard via Histonet [mailto:histonet at lists.utsouthwestern.edu] 
Sent: Tuesday, 21 April 2020 6:51 AM
To: histonet at lists.utsouthwestern.edu
Subject: [Histonet] Formalin fixation for COVID-19 positive tissues .....

How long are you fixing surgical tissue specimens from COVID-19 positive patient's before tissue processing?  I know that the CDC is recommending "72" hours for autopsy tissues, but, to me, that seems excessive for surgical pathology specimens.  Any information that you can share on this subject would be appreciated.  Thank you and stay safe.

Richard

Richard W. Cartun, MS, PhD
Director, Histology & The Martin M. Berman, MD Immunopathology/Morphologic Proteomics Laboratory Director, Biospecimen Collection Programs Assistant Director, Anatomic Pathology Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 972-1596 (Office)
(860) 545-2204 (Fax)
Richard.cartun at hhchealth.org<mailto:Richard.cartun at hhchealth.org>


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