[Histonet] Vacuolated and torn?

[Cartun, Richard]

Microtomy is so important, but often over-looked.  You might try giving the paraffin block(s) to different people and have them all cut H&Es, and then have your pathologist compare them.  If everyone's sections are suboptimal, then the problem is with fixation and/or processing.

Richard

Richard W. Cartun, MS, PhD
Director, Histology & The Martin M. Berman, MD Immunopathology & Morphologic Proteomics Laboratory
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 972-1596
(860) 545-2204 Fax



-----Original Message-----
From: Martin, Erin via Histonet [mailto:histonet at lists.utsouthwestern.edu]
Sent: Thursday, October 06, 2016 9:31 AM
To: histonet
Subject: [Histonet] Vacuolated and torn?

Good morning everyone!

One of my pathologists says that we are having a problem with the tissue on the slides looking vacuolated and torn.  He is convinced it is from microtomy.  Anyone have any ideas?  I was thinking that it might be a processing issue.



Thanks in advance!

Erin Martin, Histology Supervisor
UCSF  Dermatopathology and Oral Pathology Service
1701 Divisadero St, San Francisco, CA 94044
415-353-7248

Confidentiality Notice
The information transmitted is intended only for the person or entity to which it is addressed and may contain confidential and/or privileged material.  Any review, retransmission, dissemination or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited.  If you receive this in error please contact the sender and delete the material from any computer.
_______________________________________________
Histonet mailing list
Histonet at lists.utsouthwestern.edu
http://lists.utsouthwestern.edu/mailman/listinfo/histonet

This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure, or distribution is prohibited. If you are not the intended recipient, or an employee or agent responsible for delivering the message to the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message, including any attachments.