[Histonet] Histonet Digest, Vol 144, Issue 21: Rapid tissue Programs

[Steve McClain]

Since processing is not the issue, first standardize fixation, eg 4-6 hours before processing or in the first reagent on processor. Change that first formalin every 200 blocks or so.  When well-fixed, small tissues will tolerate rapid processing. Finally, if your pathologists can read the slides and your immunostains work, then only make small changes. And ignore the CAP.

Steve A. McClain, MD