[Histonet] tissue fixation-formaldehyde concentrations
carl.hobbs at kcl.ac.uk
Sat Jun 6 14:08:47 CDT 2015
I have to agree with the student, John.
Sure, he is coming from ignorance ( not a bad situation: naivety is not a fault... we all are/were there at some point;-)
Sure...I agree with you re the using of the word Paraformaldehyde as a fixative....
I often "sigh" when used.
However, differential fixation ( zonal fixation) has always been an issue.
We often see the zonal effects of this?
Particularly in lymph nodes ( parenchymatous tissues)
Obviously, when immersion fixing.
Most often ...NOT with agitation.
Carl Hobbs FIBMS
Histology and Imaging Manager
Guys Campus, London Bridge
Kings College London
020 7848 6813
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