Another Hallmark is the Superficial Vascular Plexus of the Skin. You can do Muscle Actin ( HHF – 35 ) or CD 34 to remark the vessels. Link to a Picture http://biologiedelapeau.fr/spip.php?page=forum&id_article=21&lang=en This Superficial Vascular Plexus allows separating Invasive Melanoma Clark´s Level III from Level IV.