[Histonet] Minimum sample size for breast markers

Rene J Buesa rjbuesa <@t> yahoo.com
Thu Sep 12 08:22:34 CDT 2013

I do not think this is the adequate forum to ask this question because you may get a wrong answer that could determine your decision. 
Your pathologist is the one who should decide about this issue.
René J.

From: Martha Ward-Pathology <mward <@t> wakehealth.edu>
To: "histonet <@t> lists.utsouthwestern.edu" <histonet <@t> lists.utsouthwestern.edu> 
Sent: Thursday, September 12, 2013 9:06 AM
Subject: [Histonet] Minimum sample size for breast markers

Is there a minimum number of cells that should be present when testing for ER, PR and Her2? I have looked on the CAP website but cannot see anything about this.  We are constantly getting these small biopsies or FNAs for testing and I sometimes wonder what the lowest threshold is for testing...20 tumor cells, 50 tumor cells????  Any information would be appreciated.  Thanks in advance for your help.
Martha Ward, MT (ASCP) QIHC

Molecular Diagnostics Lab
Medical Center Boulevard  \  Winston-Salem, NC 27157
p 336.716.2109  \  f 336.716.5890  
mward <@t> wakehealth.edu  

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