[Histonet] Tissue Processor Validation

[joelle weaver]

 On Wed, Aug 28, 2013 at 8:27 AM, Rathborne, Toni < trathborne <@t> somerset-healthcare.com> wrote: 
> > How do you validate IHC & FISH with a new processor?
 
You are going to have to revalidate IHC and FISH with new processing. How much might depend on if you are significantly changing instrumentation/technology, or just getting a new instrument of the same type. I usually don't do a full, as new assay validation, but the amount needed just to show that the processing change has not affected the test results. If there are issues that appear with that, you might have to do a complete revalidation. 




Joelle Weaver MAOM, HTL (ASCP) QIHC
 
> From: HornHV <@t> archildrens.org
> To: bbrinegarhtl <@t> gmail.com; trathborne <@t> somerset-healthcare.com
> Date: Wed, 28 Aug 2013 09:10:39 -0500
> Subject: RE: [Histonet] Tissue Processor Validation
> CC: histonet <@t> lists.utsouthwestern.edu; dianarip1 <@t> aol.com
> 
> We did the same as Beth.
> 
> Hazel Horn
> Supervisor of Histology/Autopsy/Transcription
> Anatomic Pathology
> Arkansas Children's Hospital
> 1 Children's Way | Slot 820| Little Rock, AR 72202
> 501.364.4240 direct | 501.364.1241 fax
> hornhv <@t> archildrens.org
> archildrens.org
> 
> 
> 
> 
> 
> 
> -----Original Message-----
> From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Beth Brinegar
> Sent: Wednesday, August 28, 2013 8:40 AM
> To: Rathborne, Toni
> Cc: histonet <@t> lists.utsouthwestern.edu; DianaRip1 <@t> aol.com
> Subject: Re: [Histonet] Tissue Processor Validation
> 
> Yes, we do a few validation runs. Nothing too extreme, however we gross some extra patient tissue and do a small run, then increase the amount of blocks processed until we are ready to run cases for patient diagnosis. It really only takes a week or two. After those blocks are cut, then we compare them to the previous processor results and make changes if neccessary.
> 
> Beth Brinegar HTL(ASCP)
> Anatomic Pathology Supervisor
> Mercy Medical Center
> Cedar Rapids, IA 52403
> 
> 
> On Wed, Aug 28, 2013 at 8:27 AM, Rathborne, Toni < trathborne <@t> somerset-healthcare.com> wrote:
> 
> > How do you validate IHC & FISH with a new processor?
> >
> > -----Original Message-----
> > From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:
> > histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of joelle weaver
> > Sent: Wednesday, August 28, 2013 9:23 AM
> > To: DianaRip1 <@t> aol.com; histonet <@t> lists.utsouthwestern.edu
> > Subject: RE: [Histonet] Tissue Processor Validation
> >
> > Yes definitely, 5 programs, 25-50 sister, serial sections on tissue 
> > that represents patient samples.
> >
> >
> >
> >
> > Joelle Weaver MAOM, HTL (ASCP) QIHC
> >
> > > From: DianaRip1 <@t> aol.com
> > > Date: Tue, 27 Aug 2013 22:07:19 -0400
> > > To: histonet <@t> lists.utsouthwestern.edu
> > > Subject: [Histonet] Tissue Processor Validation
> > >
> > > I am interested in knowing how many of you out there Validate your 
> > > Tissue Processors before you put them into use and how extreme you go.
> > >
> > > Diana Ripley
> > > _______________________________________________
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