[Histonet] Re: Does xylene cause skin cancer?

Jerry Ricks rosenfeldtek <@t> hotmail.com
Thu Feb 23 16:31:38 CST 2012

As far as I know Xylene is not a conformed carcinogen.  On the other hand the structure is close to that of Benzene which is a confirmed human carcinogen.  It's an aromatic hydrocarbon, so why take chances.  It makes sense to 1) minimize use. 2) Use fume hoods when possible.  3) Wear PPE--nitrile gloves not latex!






Jerry Ricks
Research Scientist
University of Washington
Department of Pathology

> Date: Thu, 23 Feb 2012 13:33:00 -0500
> From: rsrichmond <@t> gmail.com
> To: histonet <@t> lists.utsouthwestern.edu
> Subject: [Histonet] Re: Does xylene cause skin cancer?
> What's badly needed is a registry of death certificates of
> histotechnologists. The thing I'd want to examine would be the
> prevalence of myeloid leukemia and related diseases - known to be
> elevated in workers exposed to benzene. If such a correlation were
> found, it would mandate eliminating xylene from histology and cytology
> labs, and increasing precautions for handling resinous mounting media.
> The American Medical Association maintains such a registry of American
> physicians (or used to). It was used to establish that exposure to
> ionizing radiation (fluoroscopes and other X-ray equipment) was
> correlated with deaths from myeloid leukemia. Pathologists didn't have
> any particular problems - here I'd wonder about formaldehyde exposure
> and upper airway cancer. Pathologists get more exposure to
> formaldehyde than do histotechnologists.
> Bob Richmond
> Samurai Pathologist
> Knoxville TN
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