[Histonet] RE: New Cap Guidelines for Her2 and ER/PR

[Mahoney,Janice A]

We have decided to reflex to FISH those breasts that do not fall within the recommended formalin fixation time.  We do work on Saturdays so it is only the rare 3 day weekends that this comes into play.
Jan M
Omaha

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Joyce Cline
Sent: Tuesday, October 12, 2010 10:10 AM
To: histonet <@t> lists.utsouthwestern.edu
Subject: [Histonet] New Cap Guidelines for Her2 and ER/PR

Does anyone have any experience with storing formalin fixed breast tissue in 70% before processing?  I am trying to comply with the new guidelines set forth by CAP and ASCO with regard to Her2 and ER/PR and since my lab does not operate on the weekend we have been well above the 48 hour recommended formalin fixation time.  Does 70% affect antigenicity for either Her2 or ER/PR?  Any information or suggestions will be greatly appreciated.  Thanks :)


Ronda Souders
Hagerstown Medical Laboratory
301-665-4980
fax 301-665-4941
ronda.souders <@t> wchsys.org<mailto:ronda.souders <@t> wchsys.org>

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