[Histonet] AANLkTik8dnsQt16RPMSS8_x5fgqQE_18-ctUeNp71V0L@mail.gmail.com

[Andrew Burgeson]

"One thing i forgot to mention wasthat when you embed, try
to orientate the
tissue so that the long axis (if there is one) lies in the
same direction as
the cutting stroke. when embedding, orientate the tissue at
a slight
diagonal, so that the knife dous not continously pass
through the tissue on
the cutting stroke - 

(this works well for skins also, except make sure the
dermis is away from the knife)


I do not agree with the above statement about the "dermis
being embedded so as to be facing away from the blade." The
last tissue to hit the knife edge should be EPIDERMIS.
Dermis and SubQ fat should be the first tissues to hit the
blade. Perhaps this is what you meant by "dermis?"
Otherwise, I would agree with that methodology of
orientation and angle.

MethylMethacrylate bone embedding works very well from what
I understand. See link:

http://www.jhc.org/cgi/content/full/45/2/307