[Histonet] artifacts of sectioning

Tench, Bill Bill.Tench <@t> pph.org
Fri Jul 23 11:09:52 CDT 2010

It sounds like what you are describing is what we call "chatter."  it
seems to occur most frequently with GI biopsies, esp colon polyps and
usually in the abnormal epithelium.  My techs tell me that cooling the
block better on the ice block makes it go away.  i have no personal
experience, other than to say that when it occurs, it makes the slide of
very poor quality.
Bill Tench
Associate Dir. Laboratory Services
Chief, Cytology Services
Palomar Medical Center
555 E. Valley Parkway
Escondido, California  92025
Bill.Tench <@t> pph.org
Voice: 760- 739-3037
Fax: 760-739-2604

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