[Histonet] Rapid liver core biopsy processing

[Gill, Caula A.]

We handle them when we get them as frozen sections. The Pathologist are
able to give a rapid diagnosis but they do prefer the formalin fixed
tissue. 

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Garth
Fraga
Sent: Thursday, August 26, 2010 1:21 PM
To: histonet <@t> lists.utsouthwestern.edu
Subject: [Histonet] Rapid liver core biopsy processing

Dear histonetters,
 
We do about a hundred liver transplants/year at our hospital, and the
hepatologists do lots of liver core biopsies to rule out rejection.
They want a same-day diagnosis on these, so historically they have been
rush processed on a two-hour cycle (VIP machine).  They are brought over
directly from the liver biopsy suite immediately after biopsy, so they
get very little fixation in the specimen container prior to going on the
processor.  Recently we had a couple of sub-par cases and have moved to
a four-hour processing cycle.  Do any of you have any experience dealing
with rush-processed liver cores in transplant patients?  What sort of a
processing schedule do you recommend?  Anyone handling them like frozen
sections?
 
Thanks,
 
Garth Fraga (pathologist)
University of Kansas Medical Center
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