[Histonet] prefer fixative vs formalin

[Rene J Buesa]

Transfering tissues fixed in Prefer to formalin would completely "defeat" the purpose of eliminating a noxious chemical like formalin from the histology lab.
  Any tissue processor can use Prefer in the first 2 stations if you chose to do so.
  If in doubt run a paralel test of tissues fixed with botth fixatives and let the pathologist evaluate the results on a "blind" basis (fixative unknwon to them).
  Prefer has been around for many years already and is a "well known" formalin substitute.
  René J.

Heather Renko <omnivore98 <@t> yahoo.com> wrote:
  Hello Fellow Histonetters,

I am trying to eliminate some of the formalin in our lab and my safety officer has suggested that we can have our outpatient facilities and surgery department send our specimens to us in prefer and then transfer to formalin in our processor. Any experience and or thoughts on this. Additionally, what is your experience with switching over completely to prefer?? We run a normal overnight processing, no microwave processing and we do H&E, special stains, and immunohistochemistry on the Ventana platform. Thank you in advance.



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