[Histonet] general mouse-ihc-stain

[Gudrun Lang]

Hi,

perhaps not a really clever question, but I hope somebody can easily explain
it to me. Why does a (monoclonal) anti-mouse antibody stain all
mouse-tissue, when it is created against the fc-part of mouse-antibodies? Or
does this only happen with polyclonal antibodies, that are nt really
purified? Is such a secondary anti-mouse ab specific against mouse-tissue in
general? Is this just an artefact, that could be used for identifing
mouse-cells in other species? Hmmm.

 

Gudrun