[Histonet] Small endoscopy specimens

Patricia Karlisch pkarlisch <@t> psu.edu
Tue Aug 29 11:32:53 CDT 2006

  We are having occassional problems with small colon, stomach and
antrum specimens that are 'drying' out, at least this is what we think. 
The specimens show no nuclear detail and the H&E looks smudgy.   Other
specimens stained with the same slides look great.  We process our small
specimens on a short 5 hour processing schedule which seemed to have
improved some of our 85% of our specimens.  Has anyone else had this
problem?  We think that the specimen may be sitting in the OR before
they get placed in formalin. Is there any way to fix this when it
happens?  Any suggestions would be helpful.  Pat Karlisch
Pat Karlisch
Supervisor, Histology, Pathology and Laboratory Medicine
Penn State Milton S. Hershey Medical Center
Mail Code H179
Hershey, PA 17033
Phone (717) 531-6072
Fax: (717) 531- 7741
email: pkarlisch <@t> psu.edu
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