[Histonet] Her2/Neu

Rene J Buesa rjbuesa <@t> yahoo.com
Thu Nov 10 09:40:22 CST 2005


Dear Namesake:
Her2/Neu is a trade mark of DakoCytomation and it related to the human HER-2 gene , also known as NEU or ERBB2 that encodes a protein often referred to as HER2 protein or p185 
The c-erbB-2 oncoproten is closely related in structure to the epidermal growth factor and is a member of a large family of cell surface growth factor receptors. C-erbB-2 oncoprotein is present in some breast and adenocarcinomas and in some transitional cell carcinomas.
This Ab is provided by Novocastra and presents the same reaction aspect as Her2/Neu.
Her2/Neu is an FDA diagnostic approved protocol as DAKO Hercept Test  measured in 3 levels of reaction intensity with treatment prognostic value. They are essentially the same
but commercialized under different names.
Rene J.

"Till, Renee" <TillRenee <@t> uams.edu> wrote:
I am looking for a Her2/Neu antibody to use on rat tissue. I keep coming
across ErbB-2 and C-erbB-2 in relation to it. Is this the same thing? I
have found far more under the latter 2 name than under Her2 or Neu.
Thanks!



Renee' Till, HT



Arkansas Childrens Nutrition Center

1120 Marshall

Little Rock, AR 

72202



(501) 364-2774




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