[Histonet] Weighing specimens

Charles Scouten cwscouten <@t> myneurolab.com
Tue Jun 7 17:08:48 CDT 2005

Intesting.  In soft tissue, formalin shrinks the tissue by removing extracellular space, and crosslinking proteins in neighboring cells together.  It makes sense that the fluid that had been in the extracellular space is squeezed out. The tissue is smaller, and should be lighter.

Charles W.  Scouten, Ph.D. 
5918 Evergreen Blvd. 
St. Louis, MO 63134 
Ph: 314 522 0300  
FAX  314 522 0377 
cwscouten <@t> myneurolab.com 

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Barb Richmond
Sent: Tuesday, June 07, 2005 4:36 PM
To: 'histonet <@t> lists.utsouthwestern.edu'
Subject: [Histonet] Weighing specimens

Does formalin decrease the weight of tissue?  In surgery for breast reductions the tissue removed is weighing > 400 grams.  After the addition of formalin the lab is getting a weight that is 20 grams less.  The balance/scales used have been compared and they only have 2-3 gram diffrence.  What do you think?? 

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