[Histonet] best paraffin

[Bacon, Charles]

Over all of my testing I found there are several factors to consider when choosing paraffin:

1. Processor type
2. Tissue type
3. Use - embedding  vs. processing

The processor type my dictate limitations on paraffin selection. For example we were told not to use Paraplast Plus in a processor that has a stainless steel retorts as the DSMO can ruin the surface over time.
The tissue type may dictate as infiltration is different through biopsies vs. fatty breast cases. Most do well with both but you may want to factor this in during your search.
The use is the biggest deal breaker when it comes to paraffin. If there is too much plastic vs. wax it will not infiltrate during processing. If there is not enough plastic it won't section well. 
Over the years I have had good luck with several products. I loved Paraplast Plus but when we upgraded our processor we had to switch because of the stainless steel retort. I will say, we were in search of a combination paraffin that we could use for both embedding and processing. 

We settled on the product from Polyscientific: Infiltrating/Embedding Paraffin Prills (Item Number: c827)

We love it.

Chuck Bacon, HTL(ASCP)CM 
Supervisor Histology
Baystate Medical Center
361 Whitney Ave., Holyoke, MA 01040
Telephone: 413-322-4786  Fax: 413-322-4790
Charles.Bacon at baystatehealth.org

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Sent: Thursday, March 10, 2022 1:00 PM
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Subject: Histonet Digest, Vol 220, Issue 9

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