[Histonet] Fridge temp

[Charles Riley]

Some facilities run their immunostainers on a continuous basis all week
long and antibodies may never leave the machine for multiple days. The
antibody is still valid and still works. Like a previous  responder said
you can test each one and compare to previously stained slides to validate
it is still working.    I don't remember where I heard it but someone
published that for each hour an antibody is not keep within it's storage
temperature range you lose 1 day of effective usage. (so if the antibodies
were out of temp for 24 hours you lose 24 days from the printed expiration
date)

On Wed, Mar 27, 2019 at 1:24 PM MONICA D. LOCKHART via Histonet <
histonet at lists.utsouthwestern.edu> wrote:

> I agree !! The integrity of the antibody is suspect after being exposed to
> temps like that.  Even if the fridge door was kept closed during the
> outtage.
>
> Monica D. Lockhart
>
>
> -----Original Message-----
> From: WILLIAM DESALVO [mailto:wdesalvo.cac at outlook.com]
> Sent: Tuesday, March 26, 2019 7:20 PM
> To: MARY ANN; histonet at lists.utsouthwestern.edu
> Subject: Re: [Histonet] Fridge temp
>
> Simple, revalidate or pitch
>
> William DeSalvo
> ________________________________
> From: MARY ANN via Histonet <histonet at lists.utsouthwestern.edu>
> Sent: Tuesday, March 26, 2019 4:09:01 PM
> To: histonet at lists.utsouthwestern.edu
> Subject: [Histonet] Fridge temp
>
> Let's say, hypotheticaly, if you discover your fridge with all you
> antibodies and detection kits were discovered to have been at 19c. for an
> undisclosed amout of time. 12 24 48 hours due tona power surge..south
> Florida weather.
>
> Let's also propose your lab CFO/Owner dosent think its a big deal.
>
> First how would you handle the issue given the frisge has been restored ?
>
>
>
>
> Sent from Xfinity Connect Application
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-- 

Charles Riley BS  HT, HTL(ASCP)CM

Histopathology Coordinator/ Mohs