[Histonet] cross reactivity of CMV and HSV1&2 antibodies

[Taylor, Jean]

Hi everyone,

Has anyone encountered the cross reactivity of CMV and HSV1&2 in human placental tissue? We had a patient case that stained positive for these antibodies in the same tissue section. My antibody specification sheets state that there is no cross reactivity, but I have found literature that states there is.  I was wondering if any labs have experienced this staining pattern.

Thanks!
Jean Taylor, HT(ASCP)QIHC
IHC Tech
UnityPoint Health Meriter Labs
Madison WI
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