[Histonet] Radiation sterilization and IHC

Colleen Forster cforster at umn.edu
Tue Apr 24 10:16:25 CDT 2018


To do samples that you suspect prion disease also needs to be done in a
lab specifically designed for that.

I agree, formalin is sufficient.,

Colleen



On Mon, Apr 23, 2018 at 11:14 AM, Rene J Buesa via Histonet <
histonet at lists.utsouthwestern.edu> wrote:

>  I believe that is an extreme and unnecessary step. Formalin itself is an
> adequate sterilizer, the only problem would be with "prions" and
> Creutzfeldy-Jakob disease cases are not only extremely rare, but always
> known or suspected to histotechs. René.
>
>     On ‎Monday‎, ‎April‎ ‎23‎, ‎2018‎ ‎11‎:‎56‎:‎39‎ ‎AM, Mike Tighe via
> Histonet <histonet at lists.utsouthwestern.edu> wrote:
>
>  It was recently suggested to me that we might try to use our irradiator
> to sterilize (not fix) tissues rather than Formalin solution. Obviously we
> would need to validate this but has anyone tried this prior to IHC or IF?
>
> Thanks!
> Mike
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