[Histonet] Clear-Rite 3

[Bob Richmond]

Richard W. Cartun, MS, PhD - Director, Histology & The Martin M. Berman, MD
Immunopathology & Morphologic Proteomics Laboratory - Director, Biospecimen
Collection Programs - Assistant Director, Anatomic Pathology, Hartford
Hospital, Hartford, CT asks

>>Anyone using ClearRite (xylene replacement) for tissue processing?  If
so, what's been your experience?  Any effect on IHC or molecular testing?<<

>From a procedure I wrote many years ago: "A widely used aliphatic
substitute for xylene is Richard-Allan’s Clear-Rite 3™. They describe this
product as a branched chain aliphatic blend of isoparaffinic oils, a
mixture of synthetic isoparafinic [sic] aliphatic hydrocarbons, in the
chemical family of synthetic aliphatic hydrocarbons (petroleum solvent).
DOT calls the product petroleum naphtha. Its hazard label is 1 health
hazard, 3 fire hazard, 0 reactivity, no specific hazard."

This is a pretty inert material, and I wouldn't expect any special problems
with it.

"The Martin M. Berman MD" etc. - Hey, I was in residency with Marty Berman
at Johns Hopkins around 1965. I knew he went off to Connecticut but I never
heard of him again. Is he still working?

Bob Richmond

Samurai Pathologist

Maryville TN



On Sat, Jun 10, 2017 at 1:00 PM, <histonet-request at lists.utsouthwestern.edu>
wrote:

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> Date: Fri, 9 Jun 2017 17:34:14 +0000
> From: "Cartun, Richard" <Richard.Cartun at hhchealth.org>
> To: "histonet at lists.utsouthwestern.edu"
>         <histonet at lists.utsouthwestern.edu>
> Subject: [Histonet] ClearRite
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> Content-Type: text/plain; charset="us-ascii"
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> Anyone using ClearRite (xylene replacement) for tissue processing?  If so,
> what's been your experience?  Any effect on IHC or molecular testing?
> Thank you!
>
> Richard
>
> Richard W. Cartun, MS, PhD
> Director, Histology & The Martin M. Berman, MD Immunopathology &
> Morphologic Proteomics Laboratory
> Director, Biospecimen Collection Programs
> Assistant Director, Anatomic Pathology
> Hartford Hospital
> 80 Seymour Street
> Hartford, CT  06102
> (860) 972-1596
> (860) 545-2204 Fax
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