[Histonet] Her2 IHC

[Mark Tarango]

My lab does not have a written policy on this yet but are discussing it.
If the patient has a high grade tumor and HER2 IHC is 1+ (or even 0+), some
of our pathologists will reflex to FISH.  The oncologists will request it
sometimes too, more often when ER and PR are both negative.  We have found
several cases to be positive by FISH that were 0+ or 1+ by IHC.  I can't
say anything about response to HER2 therapy in this group of patients just
that they met the criteria for positive by FISH.

Mark T.
Cellnetix
Seattle, Wa

On Thu, Nov 3, 2016 at 9:12 AM, Algeo, Lacie A via Histonet <
histonet at lists.utsouthwestern.edu> wrote:

> Are any labs reflexing 1+ for FISH?
> Thanks :)
> Lacie
>
> Lacie Algeo, HTL (ASCP) MBCM
> Histology Supervisor
> Providence Sacred Heart Medical Center Laboratory
> 101 W 8th Avenue
> L-2
> Spokane, WA 99204
> 509-474-4418
> FAX 509-474-2052
> lacie.algeo at providence.org<mailto:lacie.algeo at providence.org>
>
>
> This message is intended for the sole use of the addressee, and may
> contain information that is priviledged, confidential and exempt from
> disclosure under applicable law.  If you are not the addressee, you are
> hereby notified that you may not use, copy, disclose or distribute to
> anyone the message or any information contained in the message.  If you
> have received this message in error, please immediately advise the sender
> by reply e-mail and delete this message.
>
>
> ________________________________
>
> This message is intended for the sole use of the addressee, and may
> contain information that is privileged, confidential and exempt from
> disclosure under applicable law. If you are not the addressee you are
> hereby notified that you may not use, copy, disclose, or distribute to
> anyone the message or any information contained in the message. If you have
> received this message in error, please immediately advise the sender by
> reply email and delete this message.
> _______________________________________________
> Histonet mailing list
> Histonet at lists.utsouthwestern.edu
> http://lists.utsouthwestern.edu/mailman/listinfo/histonet
>