[Histonet] formalin and shrinkage

Gudrun Lang gu.lang at gmx.at
Mon Feb 22 09:59:21 CST 2016


Today someone asked me about shrinkage caused by the fixation with
formaldehyde specially on skin-biopsies.  She spoke about shrinkage of 30%
percent. In my opinion shrinkage is mainly caused by the processing with
dehydration and defatting. Formaldehyde renders the tissue harder but not
strictly smaller. 


What is the opinion of the community?






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