[Histonet] Re: edge effect IHC

Teri Johnson TJohnson <@t> gnf.org
Wed Sep 11 11:50:36 CDT 2013

Ditto to what Tim said (as usual!) What is often referred to as "edge artifact" is sometimes excellent staining due to the edges fixed early and well, and the interior of the tissue poorly penetrated and not as well fixed. You can usually tell because the staining pattern is correct and well demarcated, and easily distinguishable from the type seen in drying artifact.

Teri Johnson
Manager, Histology
Genomics Institute for
Novartis Research
San Diego, CA

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