[Histonet] RE: Does xylene cause skin cancer?
TNMayer <@t> mdanderson.org
Thu Feb 23 07:56:33 CST 2012
We all have heard the reports that xylene causes cancer. It is a carcinogen. However only in cases where the user is extremely sensitive to xylene should you worry about a little bit getting on your skin every now and then. Don't bathe in it. Do not make it a habit. Wearing gloves (nitrile) and using other appropriate PPE should keep you safe. I wear gloves when I coverslip, change the machines and recycle. User safety is first, so check with the hospital to see what the safety department says.
Change your gloves frequently when coverslipping.
I have been a tech for 20 years and I am ok. I take the usual precautions with PPE and teach the same to my students.
Date: Wed, 22 Feb 2012 13:48:11 -0500
From: Bob Richmond <rsrichmond <@t> gmail.com>
Subject: [Histonet] Re: Does xylene cause skin cancer?
To: histonet <@t> lists.utsouthwestern.edu
<CAOKsRH671eWfT40nTOkrsQ_ZuPKn2ewxnDzvqeftBR94gVNRsQ <@t> mail.gmail.com>
Content-Type: text/plain; charset=ISO-8859-1
I don't know of any evidence that xylene causes skin cancer. Concern
is with absorption through the skin. The most likely problem is with
the bone marrow - leukemia and related diseases - from aromatic
hydrocarbons (xylene, toluene, benzene) - which of course are present
in resinous mounting media even in "xylene free" laboratories.
Latex gloves dissolve rapidly. Nitrile rubber is more resistant,
though not very. I don't know about vinyl examination gloves.
I don't wear gloves in this situation, but obviously a pathologist
gets much less exposure than a histotechnologist does. I certainly
wouldn't argue with anyone who wanted to wear them.
More information about the Histonet