[Histonet] Formalin Fixation.

[Smith, Allen]

Formalin fixation kills most but not all bacteria.  A significant percentage (~10%) of the mycobacteria present in the tissue remain viable.  Tuberculosis bacteria have been cultured from ffpe blocks.  Prions (Creutzfelt-Jacob disease) are believed to survive formalin fixation.
Allen A. Smith, Ph.D.
Professor of Anatomy
Barry University School of Podiatric Medicine

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of smitha rayadurg
Sent: Wednesday, June 22, 2011 4:14 PM
To: histonet <@t> lists.utsouthwestern.edu
Subject: [Histonet] Formalin Fixation.

 
 
Dear all
 
Does Formalin fixation of tissues kill bacteria & viruses if present in the tissue?
 
Would you please email any references on the effect of Formalin fixation on the stability of microbes (Viruses, Bacteria Parasites etc) in the tissues?
 
Grateful Thanks
Smitha.
 
 
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