[Histonet] Re: Modified GMS

[Robert Richmond]

Sheila Haas at MicroPath Laboratories, Inc. asked about substituting
periodic acid for chromic acid (because CrO3 is a significant hazmat,
I suppose).

We've discussed this on Histonet in previous years, and it's probably
in our archives. Briefly, Freida Carson several years ago showed that
periodic acid under the usual staining conditions is not a reliable
way to identify Histoplasma.

Bob Richmond
Samurai Pathologist
Knoxville TN