[Histonet] Re: [IHCRG] Hamamatsu Nanozoomer

Thu Jan 28 08:38:31 CST 2010

I would like to thank everyone that responded to my questions about these scanners.  These answers have been very valuable to my boss and I and will be taken into account when we decide on which system to purchase!
 Kim Merriam, MA, HT(ASCP)QIHC
Cambridge, MA 

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From: James Watson <JWatson <@t> gnf.org>
To: Kim Merriam <kmerriam2003 <@t> yahoo.com>
Cc: "Joel.Duckworth <@t> OLYMPUS.COM" <Joel.Duckworth <@t> OLYMPUS.COM>
Sent: Thu, January 28, 2010 9:15:52 AM
Subject: RE: [IHCRG] Hamamatsu Nanozoomer

Kim,

I use the nanozoomer a lot,  we have  scanned about 45,000 images in 3 years. I bought it because it does both fluorescence and transmitted light very well.  The aperio scanner is good and the software can view both types of scans.  The Nanzoomer software has improved greatly in the past 3 years thanks to Olympus and the service has been excellent.  I will send you some images and more information when I get to work.  I have CC’ed my sales rep,  he will make sure someone gets in touch with you today.   The cost is about the same as a single instrument from Aperio (unless aperio changed their pricing).

Jamie

From:Kim Merriam [mailto:kmerriam2003 <@t> yahoo.com] 
Sent: Thursday, January 28, 2010 4:44 AM
To: James Watson
Subject: Re: [IHCRG] Hamamatsu Nanozoomer

Thanks Jamie.  When I was at Novartis/NIBRI, I used the Aperio quite a bit (I am at Amgen now, but I remember meeting you a while back at one of the NSH meetings).  Anyway, the other Amgen sites use the Aperio, but we are intrigued by the possibility of buying one machine that can do light and IF imaging, also the Z-stack feature is a nice ad-on (although I am not sure how much we would really use it).  Based on the information I have gathered, I would be able to pull the images taken from the Nanozoomer and put them on our Aperio server for cross-site conferences.

We were actually ready to purchase the Aperio next week, but then my boss found out about the Nanozoomer, which seems to be a better instrument, but I have no idea how much it costs, I cant get anyone from Hamamatsu or Olympus to call me back.

Kim

Kim Merriam, MA, HT(ASCP)QIHC
Cambridge, MA 

________________________________

From:James Watson <JWatson <@t> gnf.org>
To: "kmerriam2003 <@t> yahoo.com" <kmerriam2003 <@t> yahoo.com>
Sent: Thu, January 28, 2010 1:08:16 AM
Subject: FW: [IHCRG] Hamamatsu Nanozoomer

Kim,

Contact me,  I have a Nanozoomer and also know a lot about the Aperio since their headquarters is near here and I have been to their office many times and they have been here.

Jamie

James Watson HT  ASCP
Facilities Manager of Histology
GNF  Genomics Institute of the Novartis Research Foundation
Tel    858-332-4647
Fax   858-812-1915
jwatson <@t> gnf.org

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu [mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Liz Chlipala
Sent: Wednesday, January 27, 2010 9:09 AM
To: kmerriam2003 <@t> yahoo.com; Histonet; ihcrg <@t> googlegroups.com
Subject: [Histonet] RE: [IHCRG] Hamamatsu Nanozoomer

Kim

We have an Aperio Scanner.  I'm not quite sure what you are asking but this is what I think from your e-mail.  Aperio scans create .svs files these files are considered a modified tiff file.  When aperio scans the file is placed into the spectrum database - from there you can create case or project files, etc.  These images can be viewed via imagescope.  There is no issue with placing other images that have not been generated on the scanscope into the spectrum database, you can upload any image into the spectrum database we have done this in the past.  These images can also be viewed with imagescope we have only uploaded single magnification tiff files into the aperio spectrum database.  The Hamamatsu Nanozoomer I believe also comes with a database and some viewing sofware.  Are you asking if you can view the HN images in the spectrum database?  To be honest I'm not sure if you can view the images completed with image scope I would ask your
 sales rep.  I'm sure you are aware that both of these scanners essentially create virtual slides.  Not just an image of a slide at one magnification.  The viewing software allows you to view the images at different magnifications. I'm not that familar with Visiomorph its the Olympus product and doesn't Olympus sell the HN scanner?  I would also think that that the database that comes with the HN scanner should be able to accept other images and should have some conferencing capabilities, I know that the aperio does.  I'm not sure if I answered your questions, but I would ask the sales reps from both aperio and Olympus about compatability.  With repects to analysis I think that the Visiomorph software will be able to analyze a image generated from the scanscope.  If you are working with an HN scanner and the visiomorph software I'm assuming that you will be able to perform batch analysis on selected images from the olympus database.  You have to
 find out if you can run batch analysis out of either of the databases with the Visiomorph software - if you have lots of slides to analyze then setting them up one at a time is too labor intensive.  You can call me if you want to, I'm at a conference but will be back in the lab tomorrow  (303) 682-3949

Liz 

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From: ihcrg <@t> googlegroups.com on behalf of Kim Merriam
Sent: Wed 1/27/2010 8:16 AM
To: Histonet; ihcrg <@t> googlegroups.com
Subject: [IHCRG] Hamamatsu Nanozoomer

Hi Everyone,

I was wondering if any of you folks had experience with the Hamamatsu Nanozoomer slide scanner.  We recently learned about it and are considering getting one instead of an Aperio slide scanner.  We plan to use Visiomorph image analysis software, so all we really need is the scanner and not all of the fancy software that these companies sell to go with their instruments.

The other labs at my company have Aperio systems and the images from the Nanozoomer would need to compatible or made to be compatabile for this to be a viable option for us (for cross-site slide conferencing purposes).  We are interested in it because this instrument can be adapted for fluorescence (with Aperio, you need to purchase 2 separate instruments; one for light microscope and one for fluorescence).

Any insights would be greatly appreciated.

Thanks,
Kim

Kim Merriam, MA, HT(ASCP)QIHC
Cambridge, MA 

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