SPAM-LOW: Re: [Histonet] COX-2

Patsy Ruegg pruegg <@t> ihctech.net
Sat Aug 29 09:43:50 CDT 2009


Richard,

I did a lot of work on cox2 a while ago on ffpe tissue and I was not ever
able to get results I was satisfied with.  I would be really interested in
this as well, sometimes it just takes finding the right clone and the right
pretreatment, I am not there yet with cox2 even though several people gave
me their protocols I could not get them to work well.

Best regards,
Patsy

Patsy Ruegg, HT(ASCP)QIHC
IHCtech
12635 Montview Blvd. Ste.215
Aurora, CO 80045
720-859-4060
fax 720-859-4110
www.ihctech.net 
www.ihcrg.org

-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Richard
Cartun
Sent: Saturday, August 29, 2009 8:14 AM
To: Lynette Pavelich; histonet <@t> lists.utsouthwestern.edu
Subject: SPAM-LOW: Re: [Histonet] COX-2

It was in "USA Today", but will be published in this week's issue of JAMA.

RWC

Richard W. Cartun, Ph.D.
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596
(860) 545-0174 Fax

>>> "Lynette Pavelich" <lpaveli1 <@t> hurleymc.com> 8/28/2009 2:37 PM >>>
Could you share the source of the study?

thank you,
Lynette

Lynette Pavelich, HT(ASCP)
Histology Supervisor
MSH Competency Coordinator
Hurley Medical Center
One Hurley Plaza
Flint, MI  48503
email: Lpaveli1 <@t> hurleymc.com 
ph:  810-257-9948
fax:  810-762-7082
>>> "Richard Cartun" <Rcartun <@t> harthosp.org> 08/28/09 2:32 PM >>>
There was a recent study that showed "aspirin" affected the growth of
one type of colorectal cancer; that which overexpresses COX-2.  If this
holds up, get ready to start doing a lot of COX-2 IHC.

Does anyone have a good mAb to COX-2 that works on formalin-fixed,
paraffin-embedded tissue that they would recommend?  Thank you.

Richard

Richard W. Cartun, Ph.D.
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596
(860) 545-0174 Fax


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