[Histonet] Intranuclear inclusions

[Secrest, Kimberly]

Hi all,
I have a pathologist who has noticed and an unusual prevelence of intranuclear inclusions in our routine H+E slides.  She's noticed it in tissue ranging from a liver biopsy to a skin biopsy.
Has anyone heard of this occuring regularly and what could cause it?

Kimberly Secrest HTL, QIHC
Histology Technical Specialist
West Virginia University Hospital