[Histonet] Chatter in GI Biopsies

mari.ann.mailhiot <@t> leica-microsystems.com mari.ann.mailhiot <@t> leica-microsystems.com
Thu Mar 8 18:28:20 CST 2007


Your chatter could come from a few places. Make sure everything is tight on
your microtome, especially the specimen head and knife holder. The other
issue or issues could be in fixing and processing. Sometimes heat and too
many 100% alcohols make biopsies brittle and/or hard and that can cause

It sounds like this just started happening, so maybe start with your
microtome and go from there.

Hope this helps.

Mari Ann Mailhiot BA HT ASCP
Application Specialist
Leica Technical Assistance Center
800 248 0123 x7267
847 236 3063 fax
mari.ann.mailhiot <@t> leica-microsystems.com

             eileen.lonergan <@t> v                                             
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                                       [Histonet] Chatter in GI Biopsies   
             03/08/2007 12:35                                              

Dear All,

We have been noticing an increase in chatter for our GI biopsies over the
last month or so.  We use both microwave (Milestone) and conventional
(VIPs) processors.  We were using the microwave mainly for small biopsies
with very good results until the increase in chatter occured.  We switched
to the conventional processors and got about the same results.  The temps
look fine as well as the solutions.   Does anyone out there have an idea on
this problem.  At this point in time, I am open to just about all
suggestions. I can be emailed at my work: mailto:elonergan <@t> convergedx.

Eileen Lonergan HT(ASCP)
ConVerge Diagnostic Services
Peabody MA 01960

Eileen Lonergan
(207) 749-9617  cell
(207) 324-6468  home

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