Her2 article in CAP Today RE: [Histonet] Joint guideline on testing for HER2 status in invasivebreast cancer

Cheryl Kerry tkngflght <@t> yahoo.com
Fri Jan 12 10:57:46 CST 2007

Hey Doug--

See if anyone in your lab subscribes to the publication "CAP Today".  The
December 06 edition has a (long) article that explains a lot of the 'why'
behind the regulations and helps interpret what is being said.  There are
short interjections by people such as Dr. Allen Gown.

This edition also sports a shorter article on the changed to streamline the
'surprise inspection' CAP that started this past summer. 

Cheryl Kerry, HT(ASCP)
Full Staff Inc.
-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Douglas D
Sent: Friday, January 12, 2007 10:10 AM
To: 'histonet'
Subject: [Histonet] Joint guideline on testing for HER2 status in
invasivebreast cancer

Has anyone had a chance to decipher this new guideline for HER2 testing? I
think that overall it is a good idea but I have an issue with appendix E. It
says that "Fixation times for needle biopsies have not been addressed."  Why
put out a guideline when the initial HER2 testing is done on the needle


It also says "Breast specimens, after appropriate gross inspection and
designation of margins, should be promptly sliced at 5- to 10-mm intervals
and fixed in formalin (unsliced samples should not be fixed). The interval
between tissue acquisition and fixation of

breast specimens should be as short as possible." Am I off on this one by
thinking that "unsliced samples should not be fixed" means that the breast
should be delivered fresh? Does this mean that the sample that is not placed
in cassettes is not to be fixed? What do you do with the unsliced/unfixed
sample then? I need some coffee! Someone straighten me out. 





Douglas D. Deltour HT(ASCP)

Histology Supervisor

Professional Pathology Services, PC

One Science Court

Suite 200

Columbia, SC 29203


Fax (803)254-3262



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