[Histonet] Use of 1% AgNO3 in gross room

Kemlo Rogerson Kemlo.Rogerson <@t> waht.swest.nhs.uk
Thu Apr 26 09:35:07 CDT 2007

Silver Nitrate
Poisonous. Causes burns. Long-term exposure can cause permanent
blue-grey staining of eyes, mouth, throat and skin, (argyria) and may
cause eye damage. Short contact can lead to deposition of black silver
stains on the skin. Very destructive of mucous membranes. Skin and eye
irritant. Experimental equivocal tumorigenic agent. 

Toxicity data 

ORL-MUS LD50 50 mg kg-1 
UNR-MAN LDLO 29 mg kg-1 
ORL-RBT LDLO 800 mg kg-1 
SCU-GPG LDLO 62 mg kg-1 
IVN-RBT LDLO 9 mg kg-1 

Would you really want a bucket of the stuff lying around for people to
dunk things into and increase the surface area for exposure?

I would suggest you carry out the procedure in a fume cupboard with
small quantities, wearing gloves and lab coat. Mind you blue-grey eyes,
mouth, throat and skin might be rather attractive.

Kemlo Rogerson
Pathology Manager
DD   01934 647057 or extension 3311
Mob 07749 754194; Pager 07659 597107;
I want it said of me by those who knew me best, that I always plucked a
thistle and planted a flower where I thought a flower would grow.
--Abraham Lincoln 

This e-mail is confidential and privileged. If you are not the intended
recipient please accept my apologies; please do not disclose, copy or
distribute information in this e-mail or take any action in reliance on
its contents: to do so is strictly prohibited and may be unlawful.
Please inform me that this message has gone astray before deleting it.
Thank you for your co-operation

More information about the Histonet mailing list