[Histonet] STP420 from Richard Allan. .
Weems, Joyce
JWEEMS <@t> sjha.org
Tue Oct 10 10:44:31 CDT 2006
Just a reminder that tissue to be used for Her2/Neu needs to be adequately fixed in formalin in order to meet FDA criteria.
And, from my research and investigation into the Xpress, I found it be excellent instrument - best suited for 24 hour labs that have thousands and thousands of specimens. I believe some 24 hour labs are able to shorten their days and have found a reduction in FTEs with the faster processing. It is a big change to adjust to!
Again my 2 cents...
Joyce
Joyce Weems
Pathology Manager
Saint Joseph's Hospital
5665 Peachtree Dunwoody Rd NE
Atlanta, GA 30342
404-851-7376 - Phone
404-851-7831 - Fax
-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu]On Behalf Of Wesley
Simms, MD
Sent: Tuesday, October 10, 2006 11:15 AM
To: Rene J Buesa; histonet <@t> lists.utsouthwestern.edu
Subject: Re: [Histonet] STP420 from Richard Allan. .
Rene,
Yes indeed, I was told last week by the nice pathologist from Miami (whose name eludes me at the moment) who Sakura brought in to teach us to use the new grossing tools that raw tissue, even if sliced at 1.5mm thick, could not be put on the machine. He quoted the 4 hour figure for breast tissue in particular. When I saw the graph of Miami's FTE staffing for HT's and pathologists by time of day (before and after Xpress), I was also puzzled as to how this would translate into any tangible benefit, either cost-wise or by improved patient care. The only result I could see was that everyone's day is going to start later and be strung out over a longer period of time. My wife, who is an attorney, summed it up best:"At least with the old processor, something was doing work overnight and being productive. Now, with the new one, nothing is."
Wesley Simms
----- Original Message -----
From: Rene J Buesa
To: Wesley Simms, MD ; histonet <@t> lists.utsouthwestern.edu
Sent: Tuesday, October 10, 2006 10:32 AM
Subject: Re: [Histonet] STP420 from Richard Allan. .
Dr. Simms:
According with Morales et al. ("inventors") you can process tissue in the Xpress that has not been previously fixed, now it turns out that you cannot?
That is another drawback yet, because it is also not true that you will be able to process 120 cassettes in 1 hour; their mathematics do not add up.
The protocol (2 stations with MW assisted protocol) + 2 "conventional" stations (just convection heating + vacuum) takes 60 minutes to complete (15 min each).
The only real advantage seems to be that you can introduce 30 cassettes every 15 minutes in the first station.
This means that you will have 30 cassettes processed in 1 hour, the following 30 (to a total of 60) the next 15 minutes (=75 minutes) and so on until you get to the 120 cassettes after 105 minutes.
And all of this has nothing to do, has not impacted at all, on the time required for manual work (grossing/cassetting, embedding, trimming and sectioning the blocks) that will amount to a total of 149 minuttes per every 30 cassettes, even allowing that there will be automated instruments to write cassetes, etch slides, routine stain and coverslip.
The "famous" 120 cassettes / hour turn out to be a total of 105 min. processing + 160 minutes of automated ancillary tasks + 596 minutes of manual work, for a grand total of 861 min =14.4 h / 120 cassettes = 2.4 FTE with 75% time utilization on 8h shifts!
I could also buy a good house with $250,000!
Just a few "numbers" about the Xpress (no reagents cost included of course!)
René J.
"Wesley Simms, MD" <wsimms <@t> mcintoshclinic.com> wrote:
By "real" time, I refer to the fact that you can't load fresh tissue on the
Xpress...even if it sliced at the requisite 1.5mm, several hours of fixation
is required (4 hours for breast). Ergo, the "real" processing time for
breast on the Xpress is five hours. In terms of cost, I have found a nice
lakefront house in the Florida panhandle and a new boat that I can buy for
the same price as an Xpress ($250,000). My informed sources also tell me to
expect quadrupled reagent costs with the Xpress, so yes, I think your use of
the term "stratosphere" is appropriate. I don't know the price of the
STP240, but I cannot imagine that it is as expensive, given that it is,
essentially, a turbocharged conventional processor. If the STP240's total
processing time is in the 5 hour ballpark, I would certainly be interested
in looking at one.
Wesley W. Simms
----- Original Message -----
From: "Jasper, Thomas G."
To: "Wesley Simms, MD"
Cc:
Sent: Monday, October 09, 2006 3:56 PM
Subject: RE: [Histonet] STP420 from Richard Allan. .
Wesley,
Could you clarify a bit? What do you mean by "real" time? And you are
certain that the two are not comparable in terms of cost. Does this mean
that the Tissue Tek Express is priced in the "stratosphere" or does it mean
that the price is justifiable due to "real" time savings? Or is the price
of the STP420 excessive because it doesn't do what the Tissue Tek Express
does? Or is it a great deal because it does process quickly at a
substantially lesser cost?
Your statement begs for more information, because I can't tell where you
stand on the issue.
Thanks,
Thomas Jasper
AP Supervisor
SMDC
Duluth, MN
-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu]On Behalf Of Wesley
Simms, MD
Sent: Monday, October 09, 2006 2:21 PM
To: histonet <@t> lists.utsouthwestern.edu
Subject: Re: [Histonet] STP420 from Richard Allan. .
How do the "real" processing times on the STP 420 compare with the Tissue
Tek Xpress? I feel certain that the two are not comparable in terms of
cost.
Wesley W. Simms
----- Original Message -----
From: "Tarango, Mark"
To: "Henry, Charlene" ;
Sent: Monday, October 09, 2006 1:56 PM
Subject: RE: [Histonet] STP420 from Richard Allan. .
Works great. I've never had a problem with it. I like that it is two
tissue processors in one (has two chambers that can be ran at the same
time). I've recently heard there are about 10 out there already.
Hopefully someone else will make a comment about it.
Mark Adam Tarango HT(ASCP)
Histology/Immunohistochemistry Supervisor
Nevada Cancer Institute
One Breakthrough Way
Las Vegas, NV 89135
mtarango <@t> nvcancer.org
Direct Line (702) 822-5112
Fax (702) 939-7663
-----Original Message-----
From: Henry, Charlene [mailto:Charlene.Henry <@t> STJUDE.ORG]
Sent: Monday, October 09, 2006 6:39 AM
To: Tarango, Mark
Subject: RE: [Histonet] STP420 from Richard Allan. .
How is the instrument performing for you?
Charlene Henry HT (ASCP), QIHC
Histology/Immunohistochemistry Section Head
Department of Pathology
St. Jude Children's Research Hospital
901-495-3191
fax 901-495-3100
-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Tarango,
Mark
Sent: Friday, October 06, 2006 2:04 PM
To: Angela Bitting; histonet <@t> lists.utsouthwestern.edu
Subject: RE: [Histonet] STP420 from Richard Allan. .
I have the STP420. The last time I heard I was the only one in the US
who has one.
Mark Adam Tarango HT(ASCP)
Histology/Immunohistochemistry Supervisor Nevada Cancer Institute One
Breakthrough Way Las Vegas, NV 89135 mtarango <@t> nvcancer.org Direct Line
(702) 822-5112 Fax (702) 939-7663
-----Original Message-----
From: histonet-bounces <@t> lists.utsouthwestern.edu
[mailto:histonet-bounces <@t> lists.utsouthwestern.edu] On Behalf Of Angela
Bitting
Sent: Friday, October 06, 2006 11:54 AM
To: histonet <@t> lists.utsouthwestern.edu
Subject: [Histonet] STP420 from Richard Allan
Has anyone had experience with this rapid tissue processor?( No vendors
please)
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