[Histonet] Endogenous Biotin and CAP regulations

[Stacy McLaughlin]

 Would anyone be willing to share how they address this issue, regarding
    CAP reg: ANP.22615 "If the laboratory uses an avidin-biotin complex
    (ABC) detection system (or a related system such as
streptavidin-biotin
    or neutravidin-biotin), is there a policy that addresses nonspecific
    false positive staining from endogenous biotin?
    We're currently using the Ventana Nexes, with biotin-streptavidin
    detection system. 
    Are there specific vendors your recommend for these reagents?
    Your answers are appreciated!
    Stacy
    Stacy McLaughlin HT (ASCP)
    Lead Tech, Histology
    Coolely Dickinson Hospital



Stacy McLaughlin HT (ASCP)
Lead Tech, Histology