[Histonet] Reproductive Toxins

John A. Kiernan jkiernan <@t> uwo.ca
Mon Mar 6 16:26:22 CST 2006

Toxins are substances produced by certain living
organisms (bacteria, fungi, snakes etc) or
released from dead ones (eg endotoxins). I don't
think any toxins are used in ordinary histology
labs. Fluorescently labelled alpha-bungarotoxin,
from a S.E.Asian krait, can be used to stain motor
endplates by binding to the nicotinic
acetylcholine receptor. This is a decidedly
"acute" neurotoxin, but the paralysis it causes
would also inhibit reproductive activities.

John Kiernan
Anatomy, UWO
London, Canada.
Angela Bitting wrote:
> Does anyone know how to tell if something in the Histo lab is a reproductive toxin or acute toxin? Some of the MSDS sheets are no help at all. Anyone else having this problem?
> Angela Bitting, HT(ASCP)
> Technical Specialist, Histology
> Geisinger Medical Center
> 100 N Academy Ave. MC 23-00
> Danville, PA 17822
> phone  570-214-9634
> fax  570-271-5916
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