[Histonet] Melanin bleach

Kemlo Rogerson kemlo.rogerson <@t> waht.swest.nhs.uk
Mon Jun 26 02:14:10 CDT 2006

Melanins are a variety of pigments and can be found in skin, brain, nerve
root ganglia and may even be classified as lipofuchsin. Some are iron free
and others contain between 50 to 60% carbon, 4 to 6.6% hydrogen, 9 to 14%
nitrogen and sulphur between 1 to 12%.

My point is that the melanins bleach at very different rates with times
ranging from 5 min for the Neuromelainins to 4 hrs for Ocular melanins with
0.25% KMNo4 at 25 degrees C. You may know when it's gone that it was melanin
but if its still there you won't know that it still could be a resistant
one, unless you stain for it afterwards.  

Kemlo Rogerson
Pathology Manager
Ext  3311
DD   01934 647057
Mob 07749 754194
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