[Histonet] lafora bodies and tau ihc

scoop <@t> mail.nih.gov scoop <@t> mail.nih.gov
Tue Dec 26 17:32:27 CST 2006

Dear All,

Does anyone have any experience/protocols for evaluating for Lafora 
bodies in mouse brain tissue?  Do you have to do electron microscopy 
and is it definitive for identification of Lafora bodies?  Also, are 
there any tricks to demonstrating tau immunohistochemically in Lafora 
bodies in mouse or any recommended anti-tau antibodies for that 
purpose?  (I can get the ubiquitin IHC to work ok)  Thanks in advance 
for any help!


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