[Histonet] Expired antibodies...for immunos..

[Joe Nocito]

only when it's convenient for the other person.

Joe
----- Original Message ----- 
From: "Bryan Hewlett" <bhewlett <@t> cogeco.ca>
To: "Joe Nocito" <jnocito <@t> satx.rr.com>; <KMB1904 <@t> aol.com>; 
<histonet <@t> pathology.swmed.edu>
Sent: Thursday, April 27, 2006 8:15 PM
Subject: Re: [Histonet] Expired antibodies...for immunos..


> Hey Joe,
>
> I'm with you!
> The disposal of a expensive, validated, working reagent, just because of 
> some mindless arbitrary date rule makes absolutely no sense!
> I thought that we were in the era of evidence-based medicine, whatever 
> happened?
>
> Bryan Hewlett
> Consultant technologist
> Anatomic Pathology
> Quality Management Program - Laboratory Services
> Ontario, Canada.
>
> ----- Original Message ----- 
> From: "Joe Nocito" <jnocito <@t> satx.rr.com>
> To: <KMB1904 <@t> aol.com>; <histonet <@t> pathology.swmed.edu>
> Sent: Thursday, April 27, 2006 6:27 PM
> Subject: Re: [Histonet] Expired antibodies...for immunos..
>
>
>> Oh boy,
>> I get to get flamed again.
>> JCAHO and CAP do not let you use expired reagents, including antibodies.
>> therefore, everyone gets to through money down the drain time and time 
>> again.
>>    I called CAP and talked to a person who got very defensive when I 
>> asked him to give the rule that says we can not use expired antibodies. 
>> He referred me to the U.S. National Register. I'm sorry, I don't have 
>> that information with right now but I'm sure someone will let me know.
>>    My beef is, if you run a known positive control with every run, you 
>> are, in essence, revalidating that antibody. Once that antibody doesn't 
>> work, replace it with one that has not expired. I know this causes a 
>> repeat and maybe a delay in reporting the results, but ask your 
>> pathologists if they would want a one day delay, or throw thousands of 
>> dollars down the sink.
>>    When I was supervising the immuno lab at the AFIP, we froze 
>> concentrated antibodies at -70 C and they still worked up to 10 years 
>> later. Now, you can't even do that. A big waste, that what it is, a big 
>> waste.
>>    Let Flaming Friday begin.
>>
>> Joe Nocito BS, HT(ASCP)QIHC
>> Histology Manager
>> Pathology Reference Lab
>> San Antonio, TX
>>
>> ----- Original Message ----- 
>> From: <KMB1904 <@t> aol.com>
>> To: <histonet <@t> pathology.swmed.edu>
>> Sent: Thursday, April 27, 2006 2:23 PM
>> Subject: [Histonet] Expired antibodies...for immunos..
>>
>>
>>> How does JCAHO handle expired antibodies if you have them...and are 
>>> using
>>> them...
>>>  Is it ok ....or not??
>>>   Kat
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>
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