AW: [Histonet] lymphatics
Andrea T. Hooper
anh2006 <@t> med.cornell.edu
Thu Oct 6 10:11:55 CDT 2005
In the mouse I do not find podoplanin to be specific for lymphatics.
I gave up on it as it also clearly stained some other fibres in the
tumor sections we were examining. This could be antibody dependent as
I only tried it from one source, although a well established source.
I know believe that Lyve-1+/Prox-1+ doublestaining is the way to go.
I believe lymphatics are currenlty being described as
Lyve-1+/Prox-1+/VEGFR-3+/Podoplanin+ although none of these markers
can be used exclusively for identification - at least in the mouse.
At 4:46 PM +0200 10/6/05, Gudrun Lang wrote:
>I think, Podoplanin is typical for lymphatic endothelcells. We purchase ours
>from Acris, Germany.
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