[Histonet] Bile Staining in Mice

[judi.ford <@t> jax.org]

I was wondering if any one could offer suggestions as to why our bile stain on mouse liver isn't working. The human positive control works well each time we run the stain, but there is no staining on any of the mouse liver tissue.  We've tried different fixes, different strains of mice, etc.   Even mice that should be very positive with bile show no positive staining. 

We're stumped........

Judi Ford
HIstotechnologist
HIstopathology & Microscopy
The Jackson Laboratory
600 Main St.
Bar Harbor, Me  04609
207-288-6193