[Histonet] Fixing question

[Christian Franci]

dear folks, pardon my ignorance but....

It seems that pressure is applied to the processing of tissues to 
ensure evenness and to force out any residual alcohol and/or xylene 
that might over-dry one's delicate samples.
I gather that depending on what machine you have you can apply pressure 
at each step or just at the final paraffin stage ( as in my case).
Here is my question... would applying pressure during the fixation of 
the tissues also be beneficial?
Would it speed up the process therefore minimizing the possibility of 
over-fixation?
Do any of you fix tissue under pressure and, if so, how do you go about 
it?  Just curious....

Cheers

Chris