[Histonet] Isopropyl alcohol and paraffin wax

[Smith, Allen]

Miscible means mutually soluble in ALL proportions.
Isopropyl alcohol and paraffin was are definitely not miscible.
However, they are mutually soluble to a limited degree.
I just did a few crude solubility estimates by eyeball in my lab:
I got about half a gram of "Paraplast" to dissolve in 100 ml of gently
boiling isopropyl alcohol.
I was able to get 30 ml of isopropyl alcohol to dissolve in 100 ml of molten
"Paraplast".
Both solutions become cloudy suspensions on cooling.
I have not tried transferring tissue directly from isopropyl alcohol to
molten paraffin, but it seems that the experiment would be worth trying.

Allen A. Smith, Ph.D.
Professor of Anatomy
School of Graduate Medical Sciences 
Barry University 
Miami Shores, FL
           
                       
                
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