Hi Joyce, We routinely fix fatty tissues (brain and fat) in Bouin's and never have a problem. Not sure if Bouin's is considered too risky to have in a clinical setting, but it'd be my first suggestion. Good luck, Sylvia Sylvia P. Poulos USDA-ARS-Animal Physiology Research Unit Athens, GA 30605 706-583-8279 706-542-0399 (fax)